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Install with the open skills CLI (global, non-interactive — available in every Claude Code session):
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill "chemical-property-lookup" -g -a claude-code -yOr manually — clone and copy the skill directory (SKILL.md + companion files):
git clone --depth 1 https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills /tmp/OpenClaw-Medical-Skills && cp -r /tmp/OpenClaw-Medical-Skills/skills/chemical-property-lookup ~/.claude/skills/chemical-property-lookupThis skill is a directory: SKILL.md is the entry point; the files below ship with it.
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# COPYRIGHT NOTICE
# This file is part of the "Universal Biomedical Skills" project.
# Copyright (c) 2026 MD BABU MIA, PhD <md.babu.mia@mssm.edu>
# All Rights Reserved.
#
# This code is proprietary and confidential.
# Unauthorized copying of this file, via any medium is strictly prohibited.
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# Provenance: Authenticated by MD BABU MIA
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---
name: chemical-property-lookup
description: Compute RDKit-driven molecular properties (MW, logP, TPSA, QED, Lipinski) for a SMILES string to support downstream drug discovery tools.
allowed-tools:
- read_file
- run_shell_command
---
## At-a-Glance
- **description (10-20 chars):** RDKit stats
- **keywords:** SMILES, RDKit, Lipinski, QED, ADMET
- **measurable_outcome:** Return a validated property summary (JSON + Lipinski verdict) for each SMILES within 60 seconds of request.
## Workflow
1. Validate SMILES input; raise explicit errors for invalid syntax.
2. Call helpers from `molecular_tools.py` (`summarize_properties`, `check_lipinski`, etc.).
3. Report MW, logP, TPSA, HBD/HBA, QED, and Lipinski pass/fail with violations.
4. Surface any calculation warnings (e.g., aromaticity perception issues).
## Guardrails
- Never infer stereochemistry; report as "not provided".
- Log invalid SMILES for manual follow-up.
- Communicate that results are screening heuristics, not definitive ADMET outcomes.
## References
- `README.md` plus `molecular_tools.py` for function signatures and dependencies.
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Gateway to 400+ bioinformatics skills from bioSkills and ClawBio. Covers genomics, transcriptomics, single-cell, variant calling, pharmacogenomics, metagenomics, structural biology, and more. Fetches domain-specific reference material on demand.
> Pharmaceutical research assistant for drug discovery workflows. Search bioactive compounds on ChEMBL, calculate drug-likeness (Lipinski Ro5, QED, TPSA, synthetic accessibility), look up drug-drug interactions via OpenFDA, interpret ADMET profiles, and assist with lead optimization. Use for medicinal chemistry questions, molecule property analysis, clinical pharmacology, and open-science drug research.