AI & LLM Integration for Claude Code

Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare datasets (MIMIC-III/IV, eICU, OMOP), or implementing deep learning models for healthcare applications (RETAIN, SafeDrug, Transformer, GNN).

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

Provides guidance for performing causal interventions on PyTorch models using pyvene's declarative intervention framework. Use when conducting causal tracing, activation patching, interchange intervention training, or testing causal hypotheses about model behavior.

Comprehensive quantum computing toolkit for building, optimizing, and executing quantum circuits. Use when working with quantum algorithms, simulations, or quantum hardware including (1) Building quantum circuits with gates and measurements, (2) Running quantum algorithms (VQE, QAOA, Grover), (3) Transpiling/optimizing circuits for hardware, (4) Executing on IBM Quantum or other providers, (5) Quantum chemistry and materials science, (6) Quantum machine learning, (7) Visualizing circuits and res

Quantizes LLMs to 8-bit or 4-bit for 50-75% memory reduction with minimal accuracy loss. Use when GPU memory is limited, need to fit larger models, or want faster inference. Supports INT8, NF4, FP4 formats, QLoRA training, and 8-bit optimizers. Works with HuggingFace Transformers.

Expert in building Retrieval-Augmented Generation systems. Masters embedding models, vector databases, chunking strategies, and retrieval optimization for LLM applications. Use when: building RAG, vector search, embeddings, semantic search, document retrieval.

Distributed training orchestration across clusters. Scales PyTorch/TensorFlow/HuggingFace from laptop to 1000s of nodes. Built-in hyperparameter tuning with Ray Tune, fault tolerance, elastic scaling. Use when training massive models across multiple machines or running distributed hyperparameter sweeps.

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

RNN+Transformer hybrid with O(n) inference. Linear time, infinite context, no KV cache. Train like GPT (parallel), infer like RNN (sequential). Linux Foundation AI project. Production at Windows, Office, NeMo. RWKV-7 (March 2025). Models up to 14B parameters.

World-class computer vision skill for image/video processing, object detection, segmentation, and visual AI systems. Expertise in PyTorch, OpenCV, YOLO, SAM, diffusion models, and vision transformers. Includes 3D vision, video analysis, real-time processing, and production deployment. Use when building vision AI systems, implementing object detection, training custom vision models, or optimizing inference pipelines.

World-class data science skill for statistical modeling, experimentation, causal inference, and advanced analytics. Expertise in Python (NumPy, Pandas, Scikit-learn), R, SQL, statistical methods, A/B testing, time series, and business intelligence. Includes experiment design, feature engineering, model evaluation, and stakeholder communication. Use when designing experiments, building predictive models, performing causal analysis, or driving data-driven decisions.

World-class ML engineering skill for productionizing ML models, MLOps, and building scalable ML systems. Expertise in PyTorch, TensorFlow, model deployment, feature stores, model monitoring, and ML infrastructure. Includes LLM integration, fine-tuning, RAG systems, and agentic AI. Use when deploying ML models, building ML platforms, implementing MLOps, or integrating LLMs into production systems.

World-class prompt engineering skill for LLM optimization, prompt patterns, structured outputs, and AI product development. Expertise in Claude, GPT-4, prompt design patterns, few-shot learning, chain-of-thought, and AI evaluation. Includes RAG optimization, agent design, and LLM system architecture. Use when building AI products, optimizing LLM performance, designing agentic systems, or implementing advanced prompting techniques.

Framework for state-of-the-art sentence, text, and image embeddings. Provides 5000+ pre-trained models for semantic similarity, clustering, and retrieval. Supports multilingual, domain-specific, and multimodal models. Use for generating embeddings for RAG, semantic search, or similarity tasks. Best for production embedding generation.

Language-independent tokenizer treating text as raw Unicode. Supports BPE and Unigram algorithms. Fast (50k sentences/sec), lightweight (6MB memory), deterministic vocabulary. Used by T5, ALBERT, XLNet, mBART. Train on raw text without pre-tokenization. Use when you need multilingual support, CJK languages, or reproducible tokenization.

Fast structured generation and serving for LLMs with RadixAttention prefix caching. Use for JSON/regex outputs, constrained decoding, agentic workflows with tool calls, or when you need 5× faster inference than vLLM with prefix sharing. Powers 300,000+ GPUs at xAI, AMD, NVIDIA, and LinkedIn.

Create and manage Claude Code skills following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns, file paths, content patterns), enforcement levels (block, suggest, warn), hook mechanisms (UserPromptSubmit, PreToolUse), session tracking, and the 500-line rule.

Multi-cloud orchestration for ML workloads with automatic cost optimization. Use when you need to run training or batch jobs across multiple clouds, leverage spot instances with auto-recovery, or optimize GPU costs across providers.

Accelerate LLM inference using speculative decoding, Medusa multiple heads, and lookahead decoding techniques. Use when optimizing inference speed (1.5-3.6× speedup), reducing latency for real-time applications, or deploying models with limited compute. Covers draft models, tree-based attention, Jacobi iteration, parallel token generation, and production deployment strategies.

Use this skill for reinforcement learning tasks including training RL agents (PPO, SAC, DQN, TD3, DDPG, A2C, etc.), creating custom Gym environments, implementing callbacks for monitoring and control, using vectorized environments for parallel training, and integrating with deep RL workflows. This skill should be used when users request RL algorithm implementation, agent training, environment design, or RL experimentation.

Query STRING API for protein-protein interactions (59M proteins, 20B interactions). Network analysis, GO/KEGG enrichment, interaction discovery, 5000+ species, for systems biology.

Expert in building Telegram bots that solve real problems - from simple automation to complex AI-powered bots. Covers bot architecture, the Telegram Bot API, user experience, monetization strategies, and scaling bots to thousands of users. Use when: telegram bot, bot api, telegram automation, chat bot telegram, tg bot.

Graph Neural Networks (PyG). Node/graph classification, link prediction, GCN, GAT, GraphSAGE, heterogeneous graphs, molecular property prediction, for geometric deep learning.

Graph-based drug discovery toolkit. Molecular property prediction (ADMET), protein modeling, knowledge graph reasoning, molecular generation, retrosynthesis, GNNs (GIN, GAT, SchNet), 40+ datasets, for PyTorch-based ML on molecules, proteins, and biomedical graphs.

Trains large language models (2B-462B parameters) using NVIDIA Megatron-Core with advanced parallelism strategies. Use when training models >1B parameters, need maximum GPU efficiency (47% MFU on H100), or require tensor/pipeline/sequence/context/expert parallelism. Production-ready framework used for Nemotron, LLaMA, DeepSeek.

Transcribe audio files to text with optional diarization and known-speaker hints. Use when a user asks to transcribe speech from audio/video, extract text from recordings, or label speakers in interviews or meetings.

Provides guidance for mechanistic interpretability research using TransformerLens to inspect and manipulate transformer internals via HookPoints and activation caching. Use when reverse-engineering model algorithms, studying attention patterns, or performing activation patching experiments.

This skill should be used when working with pre-trained transformer models for natural language processing, computer vision, audio, or multimodal tasks. Use for text generation, classification, question answering, translation, summarization, image classification, object detection, speech recognition, and fine-tuning models on custom datasets.

Trigger.dev expert for background jobs, AI workflows, and reliable async execution with excellent developer experience and TypeScript-first design. Use when: trigger.dev, trigger dev, background task, ai background job, long running task.

Use this skill for processing and analyzing large tabular datasets (billions of rows) that exceed available RAM. Vaex excels at out-of-core DataFrame operations, lazy evaluation, fast aggregations, efficient visualization of big data, and machine learning on large datasets. Apply when users need to work with large CSV/HDF5/Arrow/Parquet files, perform fast statistics on massive datasets, create visualizations of big data, or build ML pipelines that don't fit in memory.

Provides guidance for training LLMs with reinforcement learning using verl (Volcano Engine RL). Use when implementing RLHF, GRPO, PPO, or other RL algorithms for LLM post-training at scale with flexible infrastructure backends.

Voice agents represent the frontier of AI interaction - humans speaking naturally with AI systems. The challenge isn't just speech recognition and synthesis, it's achieving natural conversation flow with sub-800ms latency while handling interruptions, background noise, and emotional nuance. This skill covers two architectures: speech-to-speech (OpenAI Realtime API, lowest latency, most natural) and pipeline (STT→LLM→TTS, more control, easier to debug). Key insight: latency is the constraint. Hu

Expert in building voice AI applications - from real-time voice agents to voice-enabled apps. Covers OpenAI Realtime API, Vapi for voice agents, Deepgram for transcription, ElevenLabs for synthesis, LiveKit for real-time infrastructure, and WebRTC fundamentals. Knows how to build low-latency, production-ready voice experiences. Use when: voice ai, voice agent, speech to text, text to speech, realtime voice.

Use when the user wants to integrate with the X (Twitter) API via Xquik to search tweets, look up user profiles, extract followers, run giveaway draws, monitor accounts, or access trending topics. Also use when the user mentions 'Xquik,' 'Twitter API,' 'X API,' 'tweet scraper,' 'follower extraction,' or 'Twitter monitoring.' Covers REST API, webhooks, and MCP server setup.

| Andrej Karpathy的思维框架与表达方式。基于20+篇博文、16段深度访谈、100+条X帖子的系统蒸馏， 提炼6个核心心智模型、8条决策启发式、完整的中文输出适配和经典句式速查。 用途：作为思维顾问，用Karpathy的视角分析AI技术可靠性、学习方法、行业趋势、产品设计。 当用户提到「用Karpathy的视角」「Karpathy会怎么看」「卡帕西」「karpathy模式」时使用。 也适用于：Software 2.0/3.0讨论、vibe coding话题、神经网络训练、AI炒作判断、LLM能力边界。 即使用户只是说「从工程现实主义角度」「march of nines」「构建即理解」「锯齿状智能」也可触发。 不在用户只是普通问AI相关问题时触发——只在明确想要Karpathy式思维框架时激活。

| Ilya Sutskever的思维框架与表达方式。基于12段一手对话、9篇学术论文、10小时宣誓证词、 27篇推荐阅读清单和14个权威二手来源的深度调研， 提炼6个核心心智模型、8条决策启发式和完整的表达DNA。 用途：作为思维顾问，用Ilya的视角分析AI技术方向、安全策略、研究品味。 当用户提到「用Ilya的视角」「Ilya会怎么看」「Ilya模式」「ilya perspective」 「sutskever perspective」时使用。 即使用户只是说「帮我用Ilya的角度想想」「如果Ilya会怎么做」「切换到Ilya」也应触发。

Migrate supported instruction files, skills, agents, and MCP config into Codex project and global files.

Build a Zoom meeting bot, recorder, or real-time media workflow. Use when joining meetings programmatically, processing live media or transcripts, or combining Meeting SDK, RTMS, and backend services.