Data & Analytics for Claude Code

Production-ready microscopy image analysis and quantitative imaging data skill for colony morphometry, cell counting, fluorescence quantification, and statistical analysis of imaging-derived measurements. Processes ImageJ/CellProfiler output (area, circularity, intensity, cell counts), performs Dunnett's test, Cohen's d effect size, power analysis, Shapiro-Wilk normality tests, two-way ANOVA, polynomial regression, natural spline regression with confidence intervals, and comparative morphometry.

Comprehensive metabolomics research skill for identifying metabolites, analyzing studies, and searching metabolomics databases. Integrates HMDB (220k+ metabolites), MetaboLights, Metabolomics Workbench, and PubChem. Use when asked to identify or annotate metabolites (HMDB IDs, chemical properties, pathways), retrieve metabolomics study information from MetaboLights (MTBLS*) or Metabolomics Workbench (ST*), search for studies by keywords or disease, or generate comprehensive metabolomics research

Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics. Computes treeness, RCV, treeness/RCV, parsimony informative sites, evolutionary rate, DVMC, tree length, alignment gap statistics, GC content, and bootstrap support using PhyKIT, Biopython, and DendroPy. Performs NJ/UPGMA/parsimony tree construction, Robinson-Foulds distance, Mann-Whitney U tests, and batch analysis across gene families. Integrates with ToolUniverse for s

Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles. Creates detailed structure reports with experimental metadata, ligand information, and download links. Use when users need protein structures, 3D models, crystallography data, or mention PDB IDs (4-character codes like 1ABC) or UniProt accessions.

Production-ready RNA-seq differential expression analysis using PyDESeq2. Performs DESeq2 normalization, dispersion estimation, Wald testing, LFC shrinkage, and result filtering. Handles multi-factor designs, multiple contrasts, batch effects, and integrates with gene enrichment (gseapy) and ToolUniverse annotation tools (UniProt, Ensembl, OpenTargets). Supports CSV/TSV/H5AD input formats and any organism. Use when analyzing RNA-seq count matrices, identifying DEGs, performing differential expre

Retrieves biological sequences (DNA, RNA, protein) from NCBI and ENA with gene disambiguation, accession type handling, and comprehensive sequence profiles. Creates detailed reports with sequence metadata, cross-database references, and download options. Use when users need nucleotide sequences, protein sequences, genome data, or mention GenBank, RefSeq, EMBL accessions.

Perform statistical modeling and regression analysis on biomedical datasets. Supports linear regression, logistic regression (binary/ordinal/multinomial), mixed-effects models, Cox proportional hazards survival analysis, Kaplan-Meier estimation, and comprehensive model diagnostics. Extracts odds ratios, hazard ratios, confidence intervals, p-values, and effect sizes. Designed to solve BixBench statistical reasoning questions involving clinical/experimental data. Use when asked to fit regression

<!-- COPYRIGHT NOTICE This file is part of the "Universal Biomedical Skills" project. Copyright c 2026 MD BABU MIA, PhD <md.babu.mia@mssm.edu All Rights Reserved. This code is proprietary and confidential. Unauthorized copying of this file, via any medium is strictly prohibited. Provenance:

<!-- COPYRIGHT NOTICE This file is part of the "Universal Biomedical Skills" project. Copyright c 2026 MD BABU MIA, PhD <md.babu.mia@mssm.edu All Rights Reserved. This code is proprietary and confidential. Unauthorized copying of this file, via any medium is strictly prohibited. Provenance:

<!-- COPYRIGHT NOTICE This file is part of the "Universal Biomedical Skills" project. Copyright c 2026 MD BABU MIA, PhD <md.babu.mia@mssm.edu All Rights Reserved. This code is proprietary and confidential. Unauthorized copying of this file, via any medium is strictly prohibited. Provenance:

<!-- COPYRIGHT NOTICE This file is part of the "Universal Biomedical Skills" project. Copyright c 2026 MD BABU MIA, PhD <md.babu.mia@mssm.edu All Rights Reserved. This code is proprietary and confidential. Unauthorized copying of this file, via any medium is strictly prohibited. Provenance:

Integrate digital health data sources (Apple Health, Fitbit, Oura Ring) and connect to WellAlly.tech knowledge base. Import external health device data, standardize to local format, and recommend relevant WellAlly.tech knowledge base articles based on health data. Support generic CSV/JSON import, provide intelligent article recommendations, and help users better manage personal health data.

Search and fetch structured content from Wikipedia using the MediaWiki API for reliable, encyclopedic information

> Retrieve and analyze AlphaFold predicted structures for a protein. Use when the user provides a specific UniProt Accession ID and wants structural confidence metrics (pLDDT), domain boundary analysis, or disorder assessment. Do not use if the user only has a protein name, gene name, or amino acid sequence — ask for a UniProt ID first.

> Query and search the EMBL-EBI Ontology Lookup Service (OLS) for biomedical ontology terms, definitions, and hierarchies across 250+ ontologies (e.g., GO, DOID, HP). Use when the user asks to search for terms, retrieve details, navigate hierarchies (parents, children, ancestors), look up properties and individuals, get autocomplete suggestions, or access ontology metadata and statistics.

> Query the ENCODE Registry of cis-Regulatory Elements (cCREs) via the SCREEN GraphQL API, or make custom queries to the ENCODE Portal REST API for experiments and files (ChIP-seq peaks, etc.). Use when you want to query regulatory annotations or raw experimental data across human cell types.

> Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate file (.cif, .mmcif, or .pdb) and wants to find structurally similar proteins. Do NOT use if the user only provides a protein sequence, gene name, or UniProt ID.

> Search for scientific papers, preprints, and publications on arXiv. Extract metadata, abstracts, and download full-text PDFs or HTML versions of papers. Use when the user asks to find research papers, literature, or specific arXiv IDs.

> Search Europe PMC for scientific literature and download open-access full texts and PDFs. Retrieve full-text XML/plain text by PMCID, get citation lists and bibliography.

> Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism search, locus lookup, PubMed-linked sequences, patent protein extraction, and organism+length fallback search. Use when you need to fetch biological sequences by accession, gene name, locus tag, PubMed ID, or patent number.

> Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transparency data. Use for FDA adverse events, recalls, labeling, approvals, shortages, 510(k) clearances, NDC lookups, and any FDA safety or regulatory data query across all 28 API endpoints.

> Performs multiple sequence alignment of proteins with EBI Clustal Omega. Use when you need to align multiple sequences to assess similarity, domain conservation, or key residue conservation. Supports up to 4000 sequences and a maximum file size of 4 MB. Do not use to search for homologous proteins in a database (use MMseqs2, BLAST), align non-protein sequences (DNA, RNA), perform structural alignment (use Foldseek, PyMOL), or if you only have a single sequence.

> Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger this whenever the user provides a protein sequence or FASTA file and asks to find homologues, sequence matches, or wants to infer protein function based on sequence similarity, but not when the user wants to infer protein function based on structural similarity.

> Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or superposition, measure distances or contacts, highlight binding sites or active site residues, color by B-factor/pLDDT, or analyze protein-ligand interactions. Do not use for docking, molecular dynamics, or sequence-only analysis.

> Query the QuickGO and Evidence & Conclusion Ontology (ECO) REST API. Use this when you need to map genes to biological processes, molecular functions, or cellular components, find genes associated with a specific pathway/GO term, or explore the Gene Ontology hierarchy. Do not use for querying drug targets (use OpenTargets) or mechanistic signaling pathway diagrams (use KEGG).

> Fetch Evolutionary Conservation scores (phyloP, phastCons) and Transcription Factor Binding Sites (TFBS) from the UCSC Genome Browser. Use when analyzing whether genomic variants or regions are evolutionarily conserved, functionally important, or bounded by TF regulators across major projects (ENCODE, JASPAR, ReMap).

>- Queries the UniBind database for experimentally validated transcription factor (TF) binding sites. Use when retrieving direct TF-DNA interaction datasets, downloading binding site coordinates (BED/FASTA) for local analysis, or listing available datasets by species, cell line, or TF name. Don't use to query specific intervals, locations, genes, motif models or expression data.

> Query historical crypto market data from 0xArchive across Hyperliquid, Lighter.xyz, and HIP-3. Covers orderbooks, trades, candles, funding rates, open interest, liquidations, and data quality. Use when the user asks about crypto market data, orderbooks, trades, funding rates, or historical prices on Hyperliquid, Lighter.xyz, or HIP-3.

| Querying crypto news, newsflashes, articles, search, and on-chain market data (ETF flows, stablecoin supply, derivatives OI, M2, DXY, Bitfinex long positions, and more). Requires BLOCKBEATS_API_KEY.

Add Google Analytics 4 tracking to any project. Detects framework, adds tracking code, sets up events, and configures privacy settings.

Ad intelligence & app analytics assistant. Search ad creatives, analyze apps, view rankings, track downloads/revenue, and get market insights via api.admapix.com. Triggers: 找素材, 搜广告, 广告素材, 竞品分析, 广告分析, 排行榜, 下载量, 收入分析, 市场分析, 投放分析, App分析, 出海分析, search ads, find creatives, ad spy, ad analysis, app ranking, download data, revenue, market analysis, app intelligence, competitor analysis, ad distribution.

Complete competitive intelligence system — market mapping, product teardowns, pricing intel, win/loss analysis, battlecards, and strategic monitoring. Goes far beyond SEO to cover the full business landscape.

> Complete startup metrics command center — from raw data to investor-ready dashboards. Covers every stage (pre-seed to Series B+), every model (SaaS, marketplace, consumer, hardware), with diagnostic frameworks, benchmark databases, and board-ready reporting.

Comprehensive AI leaderboard for LLM models and AI applications. Query model rankings, model IDs, and pricing from OpenRouter, Artificial Analysis, and Pinchbench. Trigger words include "AI rankings", "LLM leaderboard", "model comparison", "AI apps ranking", "best AI models", "model benchmark", "free models", "免费模型", "OpenRouter model ID", "OpenRouter 模型", "Artificial Analysis", "artificial analysis", "AI 智力指数", "intelligence index", "coding index", "coding排行榜", "agentic index", "agentic排行榜", "模

Run Wyckoff master-style analysis from stock codes, holdings (symbol/cost/qty), cash, CSV data, and optional chart images. Use when users want online multi-source data fetching with source switching, strict Beijing-time trading-session checks, fixed system prompt analysis, single-stock analysis, holding rotation, holding add/reduce suggestions, or empty-position cash deployment suggestions.

Alpha派金融投研平台API技能，用于调用Alpha派（AlphaPai/PaiPai）的投资研究接口。覆盖五大核心能力：投研知识问答、投研数据检索、投资研究Agent（公司一页纸/业绩点评/调研大纲/主题选股/投资逻辑/可比公司/观点Challenge/行业一页纸/个股选基/主题选基/画图）、股票公告列表查询、投研图表搜索。当用户提到AlphaPai、Alpha派、PaiPai、投研问答、召回数据、公司一页纸、行业一页纸、业绩点评、调研大纲、投资逻辑、可比公司、选基、搜图表等关键词时，务必使用本skill。

> Amazon product research and seller analytics for FBA and FBM businesses. Find winning products with 14 selection strategies, track competitors, monitor BSR trends, analyze reviews, estimate monthly sales, optimize listings, and assess market opportunities. Real-time ASIN lookup with 200M+ product database. Amazon seller tools, niche research, keyword analysis, pricing strategy, and category insights powered by APIClaw API. Use when user asks about: Amazon product selection, finding products to

Cross-client analytics for Greek accounting firms. Surfaces trends, anomalies, and risks across financial data. Read-only, outputs to /data/reports/.

>- Comprehensive analysis of Uniswap Firepit burn economics: historical burn P&L, accumulation trends, fee source breakdown, competitive dynamics, and profitability projections. Governance-grade research report. Use when user asks "What's the burn economics?", "History of protocol fee burns", or "Average profit per burn."

> Finds winning Amazon products with 14 battle-tested selection strategies & 6-dimension risk assessment. Backed by 200M+ product database. Use when user asks about: product selection, finding products to sell, ASIN lookup, BSR analysis, competitor lookup, market opportunity, risk assessment, category research, pricing strategy, review analysis, listing optimization, or any Amazon seller data needs. Powered by APIClaw API (requires APICLAW_API_KEY).