Languages & Frameworks for Claude Code

DNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and execution.

Build ASP.NET Core 8+ backend services with EF Core, auth, background jobs, and production API patterns.

Use when building .NET Core applications requiring cloud-native architecture, high-performance microservices, modern C# patterns, or cross-platform deployment with minimal APIs and advanced ASP.NET Core features. Specifically:\\n\\n<example>\\nContext: Building a microservices platform with multiple .NET 10 services that need cloud-native deployment, health checks, and distributed tracing across services.\\nuser: \"I need to build a system with 5 microservices in .NET 10 using minimal APIs, each

Use this agent when working on legacy .NET Framework 4.8 enterprise applications that require maintenance, modernization, or integration with Windows-based infrastructure. Specifically:\\n\\n<example>\\nContext: User has a legacy ASP.NET Web Forms application running on .NET Framework 4.8 that needs security updates and performance optimization.\\nuser: \"We have a 10-year-old Web Forms application with ViewState bloat and some outdated security patterns. How can we modernize it without a comple

Support development of .NET MAUI cross-platform apps with controls, XAML, handlers, and performance best practices.

Perform janitorial tasks on C#/.NET code including cleanup, modernization, and tech debt remediation.

Expert in Drizzle ORM for TypeScript — schema design, relational queries, migrations, and serverless database integration. Use when building type-safe database layers with Drizzle.

Expert assistant for Drupal development, architecture, and best practices using PHP 8.3+ and modern Drupal patterns

Code Review Mode tailored for Electron app with Node.js backend (main), Angular frontend (render), and native integration layer (e.g., AppleScript, shell, or native tooling). Services in other repos are not reviewed here.

Master Electron desktop app development with secure IPC, contextIsolation, preload scripts, multi-process architecture, electron-builder packaging, code signing, and auto-update.

Use this agent when building Electron desktop applications that require native OS integration, cross-platform distribution, security hardening, and performance optimization. Use electron-pro for complete desktop app development from architecture to signed, distributable installers. Specifically:\\n\\n<example>\\nContext: A team is building a professional desktop productivity app for Windows, macOS, and Linux with auto-updates and system tray integration.\\nuser: \"We need to build a desktop note

Use this agent when you need to build fault-tolerant, concurrent systems leveraging OTP patterns, GenServer architectures, and Phoenix framework for real-time applications. Specifically:\\n\\n<example>\\nContext: Building a real-time chat application with WebSocket support, process supervision, and multi-node clustering.\\nuser: \"I need to create a Phoenix LiveView chat app with custom GenServer state management, WebSocket channels, and the ability to cluster across multiple nodes. What's the b

Write idiomatic Elixir code with OTP patterns, supervision trees, and Phoenix LiveView. Masters concurrency, fault tolerance, and distributed systems.

Use when developing firmware for resource-constrained microcontrollers, implementing RTOS-based applications, or optimizing real-time systems where hardware constraints, latency guarantees, and reliability are critical. Specifically:\\n\\n<example>\\nContext: A team is building firmware for an STM32F4-based IoT sensor that must operate on battery power for 6 months with strict latency requirements.\\nuser: \"We need firmware for a temperature/humidity sensor running on STM32F4 with 48KB RAM. Mus

Systematic error diagnosis and resolution using first-principle analysis. Use when encountering any error message, stack trace, or unexpected behavior. Supports replay functionality to record and reuse solutions.

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inferenc

Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.

Expert in event sourcing, CQRS, and event-driven architecture patterns. Masters event store design, projection building, saga orchestration, and eventual consistency patterns. Use PROACTIVELY for event-sourced systems, audit trail requirements, or complex domain modeling with temporal queries.

Expert Next.js 16 developer specializing in App Router, Server Components, Cache Components, Turbopack, and modern React patterns with TypeScript

Expert React 19.2 frontend engineer specializing in modern hooks, Server Components, Actions, TypeScript, and performance optimization

Build high-performance async APIs with FastAPI, SQLAlchemy 2.0, and Pydantic V2. Master microservices, WebSockets, and modern Python async patterns.

Turn ideas into fully formed designs and specs through natural collaborative dialogue. Use when planning new features, designing architecture, or making significant changes to the codebase.

Sets up and develops projects using Firebase products and services, especially for mobile or web apps. Covers Firebase CLI setup, project configuration, and integration with Firebase platform services.

Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.

Master Flutter development with Dart 3, advanced widgets, and multi-platform deployment.

Use when building cross-platform mobile applications with Flutter 3+ that require custom UI implementation, complex state management, native platform integrations, or performance optimization across iOS/Android/Web. Specifically:\\n\\n<example>\\nContext: Building a feature-rich social media app that needs custom animations, platform-specific native features (biometric auth, camera), and 60fps performance on both iOS and Android\\nuser: \"We need a high-performance Flutter app with custom Materi

| Use this agent when you need to review code changes in a pull request or after writing/modifying code. The agent performs comprehensive code review following established team standards, categorizing findings as Critical Issues, Suggestions, or Praise. It's particularly suited for reviewing backend (Golang/Protobuf/Postgres) and frontend (Flutter/Riverpod/GetX) code. Examples: <example> Context: After implementing a new API endpoint user: "I've added a new user profile update endpoint" assistan

Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features directory, MUI v7 styling, TanStack Router, performance optimization, and TypeScript best practices. Use when creating components, pages, features, fetching data, styling, routing, or working with frontend code.

Use when building complete frontend applications across React, Vue, and Angular frameworks requiring multi-framework expertise and full-stack integration. Specifically:\n\n<example>\nContext: Starting a new React frontend for an e-commerce platform with complex state management and real-time updates\nuser: \"Build a React frontend for product catalog with filtering, cart management, and checkout flow. Need TypeScript, responsive design, and 85% test coverage.\"\nassistant: \"I'll create a scalab

Frontend development patterns for React, Next.js, state management, performance optimization, and UI best practices.

Use this agent when you need to build complete features spanning database, API, and frontend layers together as a cohesive unit. Specifically:\\n\\n<example>\\nContext: User wants to build a new user authentication system for a web application that requires database schema, API endpoints, and frontend forms.\\nuser: \"Build a complete user registration feature with PostgreSQL schema, Node.js API endpoints, and React forms including validation and error handling.\"\\nassistant: \"I'll implement t

Use this agent when implementing game systems, optimizing graphics rendering, building multiplayer networking, or developing gameplay mechanics for games targeting specific platforms. Specifically:\\n\\n<example>\\nContext: A Unity game needs to maintain 60 FPS across mobile platforms but currently drops to 30 FPS during heavy particle effects and enemy AI pathfinding.\\nuser: \"Our game is struggling with FPS on mobile. How do we optimize without cutting features?\"\\nassistant: \"I'll profile

Specialized skill for building production-ready serverless applications on GCP. Covers Cloud Run services (containerized), Cloud Run Functions (event-driven), cold start optimization, and event-driven architecture with Pub/Sub.

Guides the usage of the Gemini API on Agent Platform with the Google Gen AI SDK for enterprise AI applications. Covers SDK usage (Python, JS/TS, Go, Java, C#), capabilities like Live API, tools, multimedia generation, caching, and batch prediction.

Python library for working with geospatial vector data including shapefiles, GeoJSON, and GeoPackage files. Use when working with geographic data for spatial analysis, geometric operations, coordinate transformations, spatial joins, overlay operations, choropleth mapping, or any task involving reading/writing/analyzing vector geographic data. Supports PostGIS databases, interactive maps, and integration with matplotlib/folium/cartopy. Use for tasks like buffer analysis, spatial joins between dat

CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bioservices.

Code review and analysis with the sardonic wit and technical elitism of Bertram Gilfoyle from Silicon Valley. Prepare for brutal honesty about your code.

| A tool for creating and managing Garry's Mod addons, including Lua scripting, content creation, and addon packaging. Use when: developing new addons, writing Lua scripts for GMod, organizing addon files, or when user mentions Garry's Mod, GMod, Lua scripting, or addon development.