Sr. UX Designer, AWS Applied AI Solutions

Role

Amazon Applied AI Solutions (AAIS) is hiring a Senior UX Designer to drive strategy and design for AI-native experiences in healthcare and life sciences. The role centers on designing, constraining, and validating agent behavior as a core UX artifact and delivering prototypes and specifications that support scientific workflows while maintaining trust, transparency, and regulatory rigor.

Key Responsibilities

• Lead design initiatives that define AI agent personas, behavioral contracts, responsibilities, boundaries, escalation behavior, citation requirements, and confidence levels.
• Identify product opportunities and resolve strategy gaps to build interoperable experiences for computational biologists, bench scientists, clinicians, and healthcare administrators.
• Craft and validate long-term design strategies through customer research, prototyping, and documentation that advocate for scientific and clinical user needs.
• Design for multiple personas and technical skill levels, covering happy paths, edge cases, error states, and high-risk situations where AI might mislead users.
• Ensure AI agents assist users with guidance, literature-based reasoning, and synthesis without replacing professional judgment.
• Use and evolve existing design systems (Trans Am, transitioning to RAD) and create domain-specific patterns, scientific visualizations, and terminology.
• Accelerate delivery through vibe coding and AI-assisted prototyping tools to create functional prototypes demonstrating complex scientific workflows.
• Conduct ethnographic studies and user research with scientists and clinicians to understand workflows, collaboration patterns, and trust requirements.
• Partner with engineering and science teams to translate prototypes into production-ready specifications and maintain alignment via regular syncs and tracking documentation.

Qualifications

Basic Qualifications

• 8+ years of design experience.
• Available online portfolio.
• Experience with design tools such as Photoshop, Illustrator, and InDesign, and prototyping in HTML, JavaScript, CSS, Ajax.

Preferred Qualifications

• Experience applying Scrum to visual or UX design processes.
• Experience designing complex workflows for specialized user groups.

Team and Context

• The team builds AI-assisted solutions tailored to scientific and healthcare users that require high precision, trust, and transparency.
• Work involves close collaboration with product managers, UX researchers, scientists, and engineers to accelerate drug discovery and improve patient outcomes.

Compensation & Locations

• Sunnyvale, CA: 156400.00 - 211600.00 USD annually
• New York, NY: 155400.00 - 210300.00 USD annually
• Seattle, WA: 137800.00 - 186400.00 USD annually
• Total compensation may include sign-on payments and restricted stock units (RSUs); final compensation depends on experience, qualifications, and location.