Sr. UX Designer, AWS Applied AI Solutions

Role

Amazon’s Applied AI Solutions (AAIS) is hiring a Senior UX Designer to join the Healthcare and Life Sciences team. The role focuses on designing AI-native experiences for scientists, clinicians, and healthcare professionals, with an emphasis on defining and validating AI agent behavior, ensuring transparency, trust, and scientific rigor.

Key Responsibilities

• Lead design initiatives to define AI agent personas, behavioral contracts, responsibilities, boundaries, escalation behavior, citation needs, and appropriate confidence levels.
• Craft and validate long-term design strategies through customer research, prototyping, and design proposals advocating for scientific and clinical users.
• Create prototypes (including AI-assisted and vibe-coded prototypes) that demonstrate complex scientific workflows and edge-case handling.
• Conduct ethnographic studies and user research with scientists and clinicians to understand workflows, collaboration patterns, and trust requirements.
• Design for multiple personas with varying technical expertise and for both happy-path and high-risk/error states.
• Leverage and extend existing design systems (Trans Am, transitioning to RAD) with domain-specific patterns, scientific visualizations, and terminology.
• Partner closely with product managers, researchers, scientists, and engineers to translate prototypes into production-ready specifications and maintain alignment through regular syncs and documentation.
• Ensure AI-assisted experiences remain transparent, trustworthy, cite sources, explain reasoning, and support (not replace) professional judgment while meeting regulatory and scientific standards.

Requirements (Basic Qualifications)

• 8+ years of design experience.
• Available online portfolio.
• Experience with design tools and prototyping technologies such as Photoshop, Illustrator, InDesign, and prototyping in HTML, JavaScript, CSS, Ajax.

Preferred Qualifications

• Experience applying Scrum to visual or UX design processes.
• Experience designing complex workflows, especially for specialized scientific or clinical domains.

Team and Context

AAIS builds AI-assisted solutions for organizations operating at the intersection of technology and human health, serving computational biologists, bench scientists, clinicians, and healthcare administrators. The team focuses on integrating agentic AI into scaled applications while maintaining precision, trust, and transparency for regulated scientific use cases.

Compensation & Benefits (summary)

The posting lists base salary ranges by location and notes additional components such as sign-on payments and restricted stock units (RSUs). Amazon provides comprehensive benefits including medical, dental, vision, prescription coverage, life and AD&D insurance, supplemental life options, employee assistance programs (EAP), mental health support, medical advice line, flexible spending accounts, adoption and surrogacy reimbursement, 401(k) matching, paid time off, and parental leave.

Locations & Stated Salary Ranges

• Sunnyvale, CA: 156,400.00 - 211,600.00 USD annually
• New York, NY: 155,400.00 - 210,300.00 USD annually
• Seattle, WA: 137,800.00 - 186,400.00 USD annually