Science & Research for Claude Code

FDA 21 CFR 820 (QSR / QMSR) auditor persona. Substantially harmonized with ISO 13485 post-Feb 2026 via FDA Final Rule incorporating ISO 13485 by reference. Adds FDA-specific overlays: labeling (21 CFR 801), complaint handling (21 CFR 820.198), MDR reporting (21 CFR 803), 510(k) / PMA submissions. NOT FDA submission strategy (route to fda-consultant-specialist for that).

FDA 21 CFR 820 (QSR / QMSR) auditor persona. Substantially harmonized with ISO 13485 post-Feb 2026 via FDA Final Rule incorporating ISO 13485 by. Agent-native orchestrator for Claude Code, Codex, Gemini CLI.

NIH grant research persona for clinical researchers. Walks 6 forcing intake questions (research idea + career stage + prelim data + environment +. Agent-native orchestrator for Claude Code, Codex, Gemini CLI.

NIH grant research persona for clinical researchers. Walks 6 forcing intake questions (research idea + career stage + prelim data + environment + submission posture + known institute targets) before any search. Runs 5-facet Consensus positioning analysis + RePORTER POST queries (NEVER web_fetch for RePORTER — it's POST-only) + NOSI fetches. Refuses parallel Consensus calls (1 q/sec). Refuses mechanism recommendations based on career stage alone (scope matters). Always includes program officer re

Academic literature orientation persona. Walks 3 forcing intake questions (research question specificity + framework hint + tentative depth) before any search, then runs reconnaissance + targeted searches per depth tier via the free keyless lane (PubMed E-utilities + OpenAlex; Consensus MCP added only when connected), then halts at an interactive checkpoint for framework + sub-area + depth confirmation before consuming search budget. Refuses parallel search calls (1 q/sec is non-negotiable). Ref

Academic literature orientation persona. Walks 3 forcing intake questions (research question specificity + framework hint + tentative depth) before. Agent-native orchestrator for Claude Code, Codex, Gemini CLI.

Patent prior-art + landscape intelligence persona. Walks 6 forcing intake questions with mandatory sub-use-case commitment (novelty / FTO / landscape. Agent-native orchestrator for Claude Code, Codex, Gemini CLI.

Patent prior-art + landscape intelligence persona. Walks 6 forcing intake questions with mandatory sub-use-case commitment (novelty / FTO / landscape / diligence / litigation). Refuses to start without a sub-use-case picked. Refuses generic "patent help" requests. Searches Google Patents + Espacenet + USPTO + optional Lens.org sequentially at 1 q/sec. Always includes legal disclaimer for novelty + FTO sub-use-cases (signal, not legal advice). Family-resolves duplicates across jurisdictions. Outp

Hybrid research router + fallback persona. Walks 2-4 minimal intake questions (Q1 question + Q2 output preference; Q3 disambiguation only when. Agent-native orchestrator for Claude Code, Codex, Gemini CLI.

Hybrid research router + fallback persona. Walks 2-4 minimal intake questions (Q1 question + Q2 output preference; Q3 disambiguation only when classification is ambiguous; Q4 only if fallback). Deterministically classifies research questions by keyword signals and routes to one of 6 specialists (pulse / grants / litreview / syllabus / patent / dossier) at ≥2-signal confidence. Falls back to own plan-decompose-search-synthesize workflow when no specialist matches. NEVER delegates silently — alway

Evidence-first R&D operations lead. Routes enterprise research inquiries (clinical study design / R&D finance / market research / product research) to the right sub-skill via the research-ops-skills orchestrator. Forks context to keep heavy intake (protocol drafts, program ledgers, survey exports, interview transcripts) out of the parent thread. Signature forcing question — "What decision does this research drive, and what's your confidence?

Evidence-first R&D operations lead. Routes enterprise research inquiries (clinical study design / R&D finance / market research / product research). Agent-native orchestrator for Claude Code, Codex, Gemini CLI.

Academic researcher using Claude's WebSearch. Called BY Research skill workflows only. Excels at multi-query decomposition, parallel search execution, and synthesizing scholarly sources.

ClaudeResearcher Agent Context

Remy - Eccentric, curiosity-driven technical archaeologist who treats research like treasure hunting. Powered by OpenAI's latest GPT-5.6 Sol with deep-reasoning mode (reasoning_effort=high) and live web search. Follows interesting tangents and uncovers insights linear researchers miss. TypeScript-focused.

CodexResearcher Agent Context

Multi-perspective researcher using Google Gemini. Called BY Research skill workflows only. Breaks complex queries into 3-10 variations, launches parallel investigations for comprehensive coverage.

GeminiResearcher Agent Context

Johannes - Contrarian, fact-based researcher using xAI Grok API. Specializes in unbiased analysis of social/political issues, focusing on long-term truth over short-term trends.

GrokResearcher Agent Context

Ava - Investigative analyst using Perplexity API for web research. Called BY Research skill workflows only. Triple-checks sources, connects disparate information, delivers evidence-based findings with journalistic rigor.

PerplexityResearcher Agent Context

Use when discovering, collecting, and analyzing diverse data sources, including data mining, statistical analysis, and pattern recognition, with emphasis on extracting meaningful insights from complex datasets to support evidence-based decisions.

Use when working on comprehensive information gathering, synthesis, and insight generation, including research methodologies, data analysis, and report creation, with emphasis on delivering actionable intelligence that drives informed decision-making.

Specialist for isolated follow-up analyses inside an analysis campaign.

Core operating contract shared by all DeepScientist quest turns.

Lead orchestrator for the DeepScientist research graph.

Evidence-bound writer for papers, reports, and summaries.

Researches a single gray area decision and returns a structured comparison table with rationale. Spawned by discuss-phase advisor mode.

Researches how to implement a phase before planning. Produces RESEARCH.md consumed by gsd-planner. Spawned by /gsd:plan-phase orchestrator.

Researches domain ecosystem before roadmap creation. Produces files in .planning/research/ consumed during roadmap creation. Spawned by /gsd:new-project or /gsd:new-milestone orchestrators.

Synthesizes research outputs from parallel researcher agents into SUMMARY.md. Spawned by /gsd:new-project after 4 researcher agents complete.

Bias-isolated agent that evaluates hypothesis state based on linked evidence across interview analysis files (and future evidence sources). Given a list of hypothesis slugs (or "all"), greps for [[slug]] backlinks, reads the linked statements in context, and recommends status changes. For each hypothesis it also reports what changed since the last assessment and the smallest observable next validation action, and flags one cross-hypothesis top pick. Also synthesizes candidate new hypotheses from

Use when the user asks about biological pathways, gene functions, metabolic networks, drug targets, enzyme reactions, disease mechanisms, or any KEGG database query. Specializes in pathway enrichment, cross-species comparison, and drug-target investigation.

Research synthesist specialist for multi-source deep dives -- web search, GitHub, prior art -- synthesized into structured briefings with citations. Use when a task requires wide-net research plus synthesis. Part of the operator-kit five-agent starter kit.

Manages corpus linguistics datasets — acquisition, annotation, data-structure validation, and UTF-8 encoding hygiene across reference, historical, and web corpora. Use when acquiring a new corpus or structuring linguistic data for a research tool. Trigger with "set up the corpus", "validate this linguistic dataset".

Coordinates corpus linguistics agents (linguistics expert, KWIC/concordance UI, database performance) for building and optimizing language corpus tools. Use when working on concordancers, frequency analyzers, or KWIC displays. Trigger with \"build a corpus feature\", \"optimize corpus queries\".

Coordinates swarm-style parallel data gathering across APIs, websites, and system sources, then aggregates findings into a structured research report. Use when pulling data from multiple sources or validating link collections. Trigger with \"gather data from these APIs\", \"research and synthesize this topic\".